NONINVASIVE FETAL GENOTYPING OF SINGLE NUCLEOTIDE VARIANTS AND LINKAGE ANALYSIS FOR PRENATAL DIAGNOSIS OF MONOGENIC DISORDERS

Noninvasive fetal genotyping of single nucleotide variants and linkage analysis for prenatal diagnosis of monogenic disorders

Abstract Background High-cost, time-consuming and complex processes of several current approaches limit the use of noninvasive prenatal diagnosis (NIPD) for monogenic disorders in clinical application.Thus, a more cost-effective and easily implementable approach is required.Methods We established a low-cost and convenient test to noninvasively dedu

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Levels of heavy metals in the environment and population exposure after five years of mineral exploration in the Las Bambas project, Peru 2010

Objectives.Determine particulate matter (PM10) and heavy metals concentrations in the environment, as well as in surrounding communities of the Las Bambas project after five years of mineral exploration.Materials and methods.A comparative cross-sectional study was conducted in three districts in the area of influence of the Las Bambas project in Ap

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